"Failed to open file. (nativePC/.../somefile.arc) 3 22"
is not a virus, not a game-breaking bug in vanilla RE5, and not random. It is always caused by a mismatch between what the game expects and what exists in nativePC . "Failed to open file
The game engine tried to access asset #22 inside archive group #3, but the file was missing, corrupted, or unreadable. but the file was missing
